Naltrexone HCI/bupropion HCI for chronic weight management in obese adults: patient selection and perspectives

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Naltrexone HCI/bupropion HCI for chronic weight management in obese adults: patient selection and perspectives

Naltrexone, an opiate antagonist, and bupropion, a noradrenergic/dopaminergic antidepressant, have many effects on the reward systems of the brain. These medications impact eating behavior, presumably via their impact on food reward. However, only bupropion induces weight loss in obese individuals, while naltrexone does not have any appreciable effect. The combination of 32 mg of naltrexone and...

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ژورنال

عنوان ژورنال: Patient Preference and Adherence

سال: 2016

ISSN: 1177-889X

DOI: 10.2147/ppa.s84778